High Quality Nootropic Ydl223c Powder CAS 489408-02-8 Hbt1

• CAS No.: 489408-02-8
• Formula: C16h17f3n4o2s
• Packaging Material: Plastic
• Storage Method: Normal
• Shelf Life: >12 Months
• Nutrient Composition: Nutrition Supplement
• Model NO.: HBT1
• Resource: Chemosynthesis
• The content of active substances: 99%
• Powder Form: White Powder
• Free Sample: Available
• Purity: Above 99%
• MOQ: 1kg
• Transport Package: 20kg/Box, 25kg/Drum
• Specification: 20kg/box, 25kg/drum
• Trademark: SCbiochem
• Origin: China
• Production Capacity: 10000kg/Monthly

Product Description

Your nootropics raw materials one-stop shop!

HBT1

HBT1 is an AMPA receptor enhancer that induces the production of brain-derived neurotrophic factor (BDNF) and has little or no excitatory effect in primary neurons. HBT1 binds to the ligand binding domain of AMPA-R in a glutamate-dependent manner.

HBT1 bound to the ligand-binding domain (LBD) of AMPA-R in a glutamate-dependent manner.?The mode of HBT1 and LY451395 binding to a pocket in the LBD of AMPA-R differed: HBT1, formed hydrogen bonds with S518 in the LBD.?Lower agonistic profile of HBT1 may associate with its lower risks of bell-shaped responses in BDNF production in primary neurons.

HBT1 Powder Base Information

Name: HBT1 powder

CAS: 489408-02-8

Purity: 98%

Chemical name: 2-(((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

Synonyms: HBT1; HBT-1; HBT 1

Molecular Formula: C16H17F3N4O2S

Molecular Weight: 386.39

Melting Point: /

Form: powder

Appearance: white to beige

Solubility: DMSO: 2 mg/mL, clear

Storage Condition: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Application: AMPA receptor potentiator

Benefits of HBT1

AMPA-R agonists, which can activate all AMPA-Rs, including resting receptors, have been shown to induce both desensitization of AMPA-R and seizure (Yamada, 1998; Beattie et al., 2000; Ehlers, 2000). AMPA-R potentiators are considered to have better pharmacological profiles because of their selective enhancement of physiologic activation of AMPA-Rs in the brain. However, AMPA-R potentiators such as LY451646, LY451395, and S18986 are reported to elicit bell-shaped responses in various pharmacological effects: LY451646 is reported to show bell-shaped responses in in vivo BDNF induction, and the bell-shaped response of LY451395 in the radial maze task was described in the introduction section of a report about LY451395 (Mackowiak et al., 2002; Bai et al., 2003; Fowler et al., 2004; Jhee et al., 2006; Bernard et al., 2010). PF-4778574 is reported to have less than a 30-fold safety margin against seizure in rodents (Shaffer et al., 2013). Thus, discovery of AMPA-R potentiators with lower risks of these issues is needed.

Dosage form application

• Pure powder form without excipients for research use.
• Tablet or capsule for /dietary supplement/prescription /nootropics use.

 

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Q: What is SCbiochem's customer base?

We provide ingredients as bulk package to retailers ,distributors,contact manufacturers with origianl drum package or OEM packages.For individual consumers,you can contact us,and we will recommend a nearest distributors to you.

Q: Why SCbiochem,What's differences?

Free samples and trial small MOQ order to verify first,for bulk orders we also have flexible payment methods and transportations method which will make sure 100% customs pass ratio,if any issues comes,we guarantee full money refund or reship one time.

Q: Where do we ship from?

We ship from several places due to destination differences,directly from China mainland by sea,air or express.DDP shipping from HongKong by UPS,DHL.Localy US warehouse domestic shipping.It's all depends on order quantity and destination.

Q: Can I request a sample of a specific ingredient before placing a bulk order?

Yes, we offer sample sizes for most of our products. You can request samples through our website, and our team will assist you in choosing the right products for your needs.

Q: How to make sure everything is pure and best?

With years experiences on Nootropics,we only work with the best and pure ones,each batch of products will have it's COA,HPLC,MS test report.You trust,we provide!

Q: What payment methods do you accept for purchases?

We accept various payment methods, including credit cards, bank transfers, paypal,and other secure online payment options. Details are available during the checkout process.

Q: How do you ensure the timely delivery of raw materials?

We work with reliable shipping partners to ensure timely and secure delivery of your orders. You can track your shipment through tracking website and our customer service team is available to assist with any delivery-related inquiries.